Overview Tesamorelin is a synthetic analogue of Growth Hormone-Releasing Hormone (GHRH) that has been the subject of extensive clinical research, including FDA-approved clinical trials for the reduction of excess visceral abdominal fat in HIV-positive patients. It is one of the most clinically validated peptides available, with a well-established mechanism and a strong body of human trial data supporting its efficacy in fat metabolism and GH optimization.
Mechanism of Action Tesamorelin binds to GHRH receptors in the anterior pituitary gland, stimulating the pulsatile release of endogenous growth hormone. Unlike exogenous GH administration, Tesamorelin works within the body’s natural feedback loops, producing a physiological GH pulse that preserves the normal regulatory mechanisms of the hypothalamic-pituitary axis. The resulting increase in GH and IGF-1 drives lipolysis — particularly in visceral adipose tissue.
Research Applications Research on Tesamorelin has focused primarily on visceral fat reduction, GH deficiency, metabolic syndrome, and body composition optimization. Clinical studies have demonstrated significant reductions in visceral adipose tissue, improvements in lipid profiles, and increases in lean body mass. It has also been studied for its potential cognitive benefits, including improvements in memory and executive function in older adults.
Reconstitution & Storage Tesamorelin is supplied as a lyophilized powder. Reconstitute by adding bacteriostatic water slowly along the inner wall of the vial. Once reconstituted, keep refrigerated.
Tesamorelin (10mg) — Visceral Fat Loss & GH Pulse comes as a lyophilized powder and must be reconstituted before use.
You’ll need bacteriostatic water and insulin syringes,
both available for purchase as add-ons below.
Join our email list for exclusive offers and the latest news.
Choosing a selection results in a full page refresh.
Opens in a new window.
Age & Research Use Confirmation
By accessing this website and purchasing from Greyline Peptides, you confirm and agree that:
All products sold are intended strictly for laboratory research purposes only
Products are not intended for human or veterinary use
Products are not drugs, supplements, or therapeutic agents
Products have not been approved by Health Canada for medical use
You are purchasing as a qualified researcher, institution, or laboratory entity, or on behalf of one
You are 19 years of age or older.
Any dosing reference materials provided are compiled from publicly available research literature and are intended solely to support laboratory research protocols. They do not constitute medical advice, prescriptions, or recommendations for human use.
By proceeding, you acknowledge that you assume full responsibility for the lawful handling and use of these research materials in accordance with all applicable federal, provincial, and territorial laws and regulations.
