Overview SS-31 (also known as Elamipeptide or MTP-131) is a cell-permeable tetrapeptide that specifically targets and protects the inner mitochondrial membrane. It is considered one of the most advanced mitochondria-targeted compounds in research today, with a growing body of evidence supporting its role in protecting against age-related mitochondrial dysfunction, oxidative stress, and cellular energy decline.
Mechanism of Action SS-31 selectively concentrates in the inner mitochondrial membrane where it binds to cardiolipin — a phospholipid critical for maintaining mitochondrial structure and electron transport chain efficiency. By stabilizing cardiolipin and reducing mitochondrial reactive oxygen species (ROS) production, SS-31 preserves ATP synthesis, prevents mitochondrial permeability transition, and protects cells from apoptosis under conditions of metabolic stress.
Research Applications Research on SS-31 has explored its role in protecting cardiac tissue during ischemia-reperfusion injury, reducing age-related mitochondrial dysfunction, improving skeletal muscle performance in sarcopenia models, and supporting kidney function in acute kidney injury. It has also been studied in the context of neurodegenerative diseases, heart failure, and metabolic syndrome.
Reconstitution & Storage SS-31 is supplied as a lyophilized powder. Reconstitute by adding bacteriostatic water slowly along the inner wall of the vial. Store unreconstituted vials refrigerated and away from direct light. Once reconstituted, keep refrigerated.
SS-31 / Elamipeptide (10mg) — Mitochondrial Protection comes as a lyophilized powder and must be reconstituted before use.
You’ll need bacteriostatic water and insulin syringes,
both available for purchase as add-ons below.
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Age & Research Use Confirmation
By accessing this website and purchasing from Greyline Peptides, you confirm and agree that:
All products sold are intended strictly for laboratory research purposes only
Products are not intended for human or veterinary use
Products are not drugs, supplements, or therapeutic agents
Products have not been approved by Health Canada for medical use
You are purchasing as a qualified researcher, institution, or laboratory entity, or on behalf of one
You are 19 years of age or older.
Any dosing reference materials provided are compiled from publicly available research literature and are intended solely to support laboratory research protocols. They do not constitute medical advice, prescriptions, or recommendations for human use.
By proceeding, you acknowledge that you assume full responsibility for the lawful handling and use of these research materials in accordance with all applicable federal, provincial, and territorial laws and regulations.
