{"product_id":"ll-37","title":"LL-37 (5mg) — Antibiotic \u0026 Infection-Fighting Peptide","description":"\u003cp\u003e \u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eKey Health Benefits:\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ch6\u003e\u003cstrong\u003eStrengthens the immune system\u003c\/strong\u003e\u003c\/h6\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ch6\u003e\u003cstrong\u003eReduce chronic inflammation\u003c\/strong\u003e\u003c\/h6\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ch6\u003e\u003cstrong\u003ePromotes wound healing\u003c\/strong\u003e\u003c\/h6\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ch6\u003e\u003cstrong\u003eSupports gut health\u003c\/strong\u003e\u003c\/h6\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ch6\u003e\u003cstrong\u003eImproves skin health\u003c\/strong\u003e\u003c\/h6\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eOverview\u003cbr\u003eLL-37 is the only member of the cathelicidin family of antimicrobial peptides found in humans, making it one of the most important components of the innate immune system. It is produced naturally by immune cells, epithelial cells, and skin cells in response to infection and inflammation. Research on LL-37 has revealed a remarkably broad spectrum of biological activity — from direct antimicrobial action to wound healing, immune modulation, and even anti-cancer properties.\u003c\/p\u003e\n\u003cp\u003eMechanism of Action\u003cbr\u003eLL-37 exerts its antimicrobial effects by disrupting the cell membranes of bacteria, fungi, and enveloped viruses through electrostatic interaction with negatively charged microbial membranes. Beyond direct killing, it acts as an immune modulator by stimulating the recruitment of immune cells to sites of infection, promoting angiogenesis, and activating toll-like receptor signaling pathways. It also promotes epithelial cell migration and proliferation, directly contributing to wound closure.\u003c\/p\u003e\n\u003cp\u003eResearch Applications\u003cbr\u003eResearch on LL-37 has focused on its broad-spectrum antimicrobial activity against drug-resistant bacteria (including MRSA), antiviral properties, wound healing acceleration, anti-biofilm activity, and immune system modulation. It has also been studied in the context of cancer research, where it has demonstrated selective cytotoxicity against certain tumor cell lines, and in inflammatory skin conditions such as psoriasis and rosacea.\u003c\/p\u003e\n\u003cp\u003eReconstitution \u0026amp; Storage\u003cbr\u003eLL-37 is supplied as a lyophilized powder. Reconstitute by adding bacteriostatic water slowly along the inner wall of the vial. Store unreconstituted vials away from direct light. Once reconstituted, keep refrigerated.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0698\/5983\/5978\/files\/Greyline_LL37_5mg_Guide.pdf?v=1779507931\"\u003eDownload Dosing Guide\u003c\/a\u003e\u003c\/p\u003e","brand":"Greyline Peptides","offers":[{"title":"5mg","offer_id":43390387257418,"sku":"LL37-5MG","price":60.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0698\/5983\/5978\/files\/IMG-4280.png?v=1777517254","url":"https:\/\/greylinepeptides.com\/products\/ll-37","provider":"Greyline","version":"1.0","type":"link"}